Staying positive with multiple sclerosis: How can you protect your mental health?
Published Mar 7, 2025 • By Candice Salomé
Multiple sclerosis (MS) doesn’t just affect the body, it can also take a toll on mental health.
How does this condition impact emotional well-being? What are the main psychological challenges patients face? What strategies can help manage emotions and maintain a positive mindset? And when should professional support be considered?
In this article, we’ll explore the connection between MS and mental health, along with practical tips for coping with the emotional challenges of living with this condition.

What is multiple sclerosis (MS)?
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system, including the brain and spinal cord. It is characterized by the deterioration of myelin, the protective sheath surrounding nerve fibers, which disrupts the transmission of nerve signals.
MS affects approximately 2.8 million people worldwide and is more prevalent in women. Symptoms vary greatly from person to person and may include fatigue, vision problems, coordination and balance issues, and cognitive difficulties.
Managing MS involves treatments aimed at modulating the immune system, alleviating symptoms, and improving quality of life. Therapeutic options include immunomodulatory drugs, corticosteroids to reduce inflammation, and rehabilitation therapies to help maintain mobility and independence.
How does MS impact mental health?
MS is an inflammatory disease of the central nervous system that can cause a wide range of symptoms, including motor, visual, and cognitive impairments, as well as extreme fatigue. Beyond these physical challenges, the condition can also take a significant toll on mental well-being.
Emotional stress and uncertainty
Living with MS often involves coping with the uncertainty of disease progression, daily challenges, and shifts in self-perception. This can lead to increased stress and social isolation.
Neurological effects on mental health
Since MS affects the central nervous system, it can directly impact mental health. Lesions in certain areas of the brain may interfere with emotional regulation and mood, making a person more vulnerable to anxiety and depression.
Chronic fatigue
Persistent fatigue, one of the most common symptoms of MS, can make it harder to manage emotions and maintain an active social life. This can lead to withdrawal from social interactions, further intensifying feelings of isolation.
Stigma and societal perception
Misconceptions about MS and the reactions of others can also contribute to self-isolation. Some people may struggle with the fear of being misunderstood or judged, which can make it more difficult to seek support.
Several studies have highlighted a strong link between MS and an increased risk of anxiety and depression, reinforcing the importance of addressing mental well-being alongside physical health.
How can you improve your mental health while living with MS?
Acknowledge your emotions
Facing a chronic illness like MS often brings a mix of emotions: anger, frustration, sadness, fear, etc. Instead of suppressing these feelings, it can be helpful to acknowledge and express them through writing, talking, or creative activities.
Seek social support and avoid isolation
Having a strong support system plays a vital role in mental well-being. Staying connected with loved ones, joining support groups, or participating in online forums like Carenity can help MS patients share their experiences, exchange advice, and feel understood.
Engage in suitable physical activity
Exercise, even in a gentle form, can boost mood and energy levels. Depending on individual abilities, activities like walking, swimming, yoga, or breathing exercises can help reduce stress and improve sleep quality.
Practice relaxation techniques
Mindfulness meditation, deep breathing exercises, and techniques like sophrology can be effective in managing anxiety and moments of tension.
Create a balanced daily routine
Listening to your body and adjusting your daily rhythm is essential. Organizing activities with built-in rest periods, planning enjoyable moments (hobbies, creative pursuits, time in nature), and avoiding mental overload can all contribute to better emotional well-being.
When should you seek professional help for mental health with MS?
Sometimes, despite best efforts, emotional struggles persist. In such cases, seeking support from a healthcare professional, such as a psychologist, psychiatrist, or stress management coach, can be beneficial.
There are various forms of professional support, depending on individual needs:
- Cognitive behavioral therapy (CBT): Helps manage anxiety and negative thought patterns.
- Support groups: Provides opportunities to connect with others facing similar experiences.
- Patient associations: Some organizations offer specialized support for people with MS.
- Medication, if needed: A healthcare provider may recommend treatment options to stabilize mood and reduce anxiety when necessary.
It's important to remember that every person’s experience with MS is unique. What works for one person may not be effective for another. The key is to find strategies that help you feel better and move forward at your own pace.
Key takeaways
MS can have a significant impact on mental health, particularly due to chronic fatigue and the uncertainty of disease progression. Accepting and expressing emotions is essential to coping with the psychological challenges of MS. Social support from family, friends, and patient communities helps prevent isolation and provides emotional encouragement. Physical activity and relaxation techniques can improve mood and reduce stress. If emotional issues persist, consulting a healthcare professional can provide valuable support to regain balance and enhance overall well-being.
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Sources :
La sclérose en plaques (SEP), APF France Handicap
Les troubles psychologiques au cours de la SEP, SEP Ensemble
Sclérose en plaques : l'impact sur la santé mentale, Sanofi
Éclairage: Les troubles de santé mentale liés à la sclérose en plaques, SP Canada
Les aspects psychologiques de la SEP, Fondation Charcot Stichting
SEP et psychothérapie : une prise en charge de la santé mentale au-delà des traitements médicamenteux, SEP Ensemble